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Neutral Pharmaceutical Glass Tube with Great Hydrolytic Resistance Performance

Two clear glass tubes and three amber glass tubes are displayed.
Pharmaceutical glass tube plays a major role in the manufacturing process of pharmaceutical parental containers.

Neutral Pharmaceutical Glass Tube commonly refers to tubes made from neutral borosilicate glass with a coefficient of mean linear thermal expansion of 5.0. Generally, it has exceptional chemical stability and high heat resistance to thermal shock and sudden temperature change. It is typically used as a raw material by the pharmaceutical packaging companies to manufacture primary packaging products and plays a major role in the manufacturing process of pharmaceutical parental containers.

  • Both clear and amber glass tubes are available
  • High chemical resistance
  • Great hydrolytic resistance
  • Compliance with ISO 719 standards
  • Customized glass tubes are available
  • Special discount for large orders and various promotion campaigns

Features

Main Composition (%)
SiO2 B2O3 Na2O BaO CaO AI2O3
73 10 7 2 1 6
Physical properties
Coefficient of mean linear thermal expansion at (20 °C; 300 °C) acc. to ISO 7991 4.9 × 10-6 K-1
Transformation temperature Tg 515 °C
Glass temperature at annealing point logη=13 535 °C
Glass temperature at soft point logη=7.6 783 °C
Glass temperature at working point logη=4 1020 °C
Density p at 25 °C 2.32 g/cm3
Chemical properties
Hydrolytic resistance Class
Acc. to ISO 719 HGB1
Acc. to USP 25 Type I
Acid resistance A I
Alkali reistance A2

Limit Values in the Hydrolytic Resistance Grains Test (Boiling Water Test)

Class Consumption of hydrolytic acid solution (4.2) per gram of glass grains (ml/g) Equivalent of alkali expressed as mass of sodium oxide (Na2O) per gram of glass grains (μg/g)
HGB1 Up to and including 0.10 Up to and including 31
HGB2 From 0.10 up to and including 0.20 From 31 up to and including 62
HGB3 From 0.20 up to and including 0.85 From 62 up to and including 264
HGB4 From 0.85 up to and including 2.0 From 264 up to and including 620
HGB5 From 2.0 up to and including 3.5 From 620 up to and including 1085
Notes: "HGB" stands for the hydrolytic resistance of glass grains according to the boiling water test method.

Benefits

  • High chemical resistance, neutrality, leak-tightness and stability
  • Optional glass-tube coating for protection against scratches
  • Application-specific cutting of tube ends
  • Protection from contamination during transport and processing into flasks and ampoules

Specification

Outside Diameter Range (mm) Wall Thickness Range (mm) Outside Diameter Tolerance (mm) Wall Thickness Tolerance (mm)
6.0–8.9 0.60–0.95 ±0.15 ±0.03
1.00–1.15 ±0.15 ±0.04
1.20–1.40 ±0.20 ±0.04
9.0–13.5 0.50–0.55 ±0.13 ±0.02
0.60–1.00 ±0.15 ±0.03
1.05–1.35 ±0.20 ±0.04
1.40–1.50 ±0.25 ±0.05
13.6–15.5 0.50–0.55 ±0.13 ±0.02
0.60–1.00 ±0.18 ±0.03
1.10–1.35 ±0.20 ±0.04
1.40–1.50 ±0.25 ±0.05
15.6–19.9 0.50–0.60 ±0.15 ±0.03
0.65–1.35 ±0.20 ±0.04
1.40–1.60 ±0.30 ±0.05
20.0–23.5 0.55–1.20 ±0.20 ±0.04
1.25–1.35 ±0.24 ±0.05
1.40–1.60 ±0.30 ±0.06
23.6–24.9 0.55–1.05 ±0.20 ±0.04
1.10–1.35 ±0.24 ±0.05
1.40–1.60 ±0.30 ±0.06
25.0–28.0 0.55–0.65 ±0.25 ±0.04
1.10–1.35 ±0.25 ±0.05
1.40–1.60 ±0.30 ±0.06
28.1–29.9 0.55–1.05 ±0.25 ±0.04
1.10–1.35 ±0.25 ±0.05
1.40–1.60 ±0.30 ±0.06
30.0–32.0 1.00–1.35 ±0.30 ±0.05
1.40–1.50 ±0.40 ±0.08

Application

Pharmaceutical glass tubes are commonly used to produce high-quality vials, ampoules and cartridges for the primary pharmaceutical packaging made of neutral borosilicate glass.

Several pharmaceutical glass vials are displayed.
Glass vials made of pharmaceutical glass tubes.
Several pharmaceutical glass ampoules are displayed.
Glass ampoules made of pharmaceutical glass tubes.
Several pharmaceutical glass cartridges are displayed.
Glass cartridges made of pharmaceutical glass tubes.
Several kinds of pharmaceutical glass containers are displayed.
Various glass containers made of pharmaceutical glass tubes.

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LingYan Engineering Co., Ltd.
E-mail: sales@glass-product.com

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